Everything about IP-6
IP-6 is a naturally occurring component of plant fiber.
IP-6, also known as phytate, is associated with dietary fiber and thus is naturally present in a wide variety of plant foods, especially wheat bran, whole grains, and legumes. Usual dietary intakes range from 1–1.5 grams phytate per day.
While there is no dietary requirement for IP-6, people consuming diets low in dietary fiber and nuts and seeds have the lowest intake.
Kidney stones
Phytate in foods has been associated with reduced mineral absorption. In particular, significant interference with iron absorption has been reported. People who are iron deficient should talk with a doctor before supplementing with IP-6. Even for those who are not iron deficient, if IP-6 supplements are taken for more than several months and fatigue a possible symptom of iron deficiency develops, a doctor should be consulted. How much iron supplementation (if any) should be used to counteract the iron-depleting effect of IP-6 varies from person to person, though many people are likely to not require such supplementation. At the time of writing, there were no well-known drug interactions with IP-6.
Virtually all research suggesting beneficial effects from taking IP-6 involve animals and not people. It is not known whether IP-6 would be useful for humans or if so, what would be the optimal amount.